P. Rocca, E. Cocuzza, R. Rasetti, L. Ravizza, E. Zanalda, F. Bogetto - Vol. 7, Marzo 2001, num.1
Testo Immagini Bibliografia Summary Riassunto Indice
This study evaluated 126 liver transplantation candidates for the presence
of psychiatric disorders. In addition we tried to examine the relationship
between psychiatric diagnosis and the etiology of liver failure.
Psychiatric diagnosis were made on the basis of the structured clinical interview
for DSM-IV (SCID). Patients were also assessed with the Hamilton Depression
Rating Scale (HDRS) and the Spielberger Anxiety Inventory, State and Trait
forms (STAI-X1 and STAI-X2). Neuropsychological screening was carried-out
using the Mini Mental State Examination (MMSE), the Trailmaking Tests A and
B and the Digit Span, a subtest of the Wechsler Adult Intelligence Scale (WAIS).
Forty-three percent of the subjects had al least one psychiatric diagnosis.
Adjustment disorders were the most common diagnoses (80%). Patients with HCV
were more likely to have psychiatric disorder with depression (48%). About
40% of the subjects had mild cognitive impairment.
Our data suggest a high rate of psychiatric disorders, particularly of adjustment
disorders, in liver transplantation candidates. Furthermore depressive symptoms
are prevalent in HCV patients.