M. Meduri, C. Cedro, M.R.A. Muscatello, G. Pandolfo, R. Russo, A.E. Di Rosa, R. Zoccali - Vol. 5, Settembre 1999, num.3
Testo Immagini Bibliografia Summary Riassunto Indice
I sintomi ossessivo-compulsivi quale
possibile aspetto deimensionale del disurbo schizofrenico: aspetti clinici
e risposta al trattamento con SSRI
Obsessive-compulsive symptoms as a possible
dimensional feature of schizophrenic disorder: clinical features and response
to treatment with SSRIs
Objective: obsessive-compulsive (OC) symptoms in schizophrenic patients have been described for more than a century; recent studies stressed high prevalence rates and worse outcome in the group of patients with OC symptoms. We evaluated the response to treatment with SSRIs in schizophrenic patients with OC symptoms.
Method: 15 schizophrenic patients with OC symptoms were evaluated. All subjects were treated with classic and atypical antipsychotic drugs showing a good stabilization of psychotic symptoms. An additional treatment with SSRIs was carried out.
Results: a significant clinical improvement of OC symptoms was observed after SSRI introduction.
Conclusion: OC symptoms may represent a new dimensional feature of schizophrenic disease. This symptomatology is resistant to NL, but it seems to be responsive to SSRIs.