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S. Bellino, E. Paradiso, C. Zanon, F. Bogetto - Vol. 10, June 2004, Issue 2

Testo Immagini Bibliografia Summary Indice

Relazione tra life-event ed episodio depressivo maggiore in pazienti con disturbo borderline di personalità
Relationship between life-events and major depressive episode in patients with borderline personality disorder

Objective
nvestigations of relationship between major events in patient’s life and borderline personality disorder (BPD) showed a likely association with childhood traumatic experiences while the role of stressors in adulthood remains unclear. The aim of our study is to compare number, severity and type of life-events (LE) in the 6 months before the onset of a major depressive episode (MDE) between two subgroups of patients with BPD and with other personality disorders (PDs).

Methods
153 consecutive outpatients with a diagnosis of personality disorder who presented a MDE were included and divided in two subgroups: with BPD and with other PDs. LE occurred in the 6 months before the onset of MDE were identified using the Paykel’s List of Recent Life Events.
Statistical analysis was performed using Student t-test to compare the frequency of events most commonly found in BPD patients.

Results
No significant differences of number and severity of LE were found between subgroups, although BPD patients showed a trend for a higher number and a lower score of stressors.
Considering the most common events in BPD subgroup, two of them showed a significant difference if compared with the control subgroup with other PDs: increased arguments with resident family members (p = 0,0005) and hospitalization of family member (serious illness) (p = 0,002).

Conclusions
LE preceding the onset of MDE in borderline patients do not significantly differ from the control group. On the contrary, a significant association was found between BPD and events of conflict and loss that appear related to the psychopathology of the disorder.