P. ROCCA, S. BELLINO, L. MARCHIARO, L. PATRIA, R. RASETTI, F. BOGETTO - Vol. 9, September 2003, Issue 2
Testo Immagini Bibliografia Summary Indice
La depressione nel corso della schizofrenia:
indagine su un campione di soggetti schizofrenici
con l’utilizzo di scale di valutazione specifiche
Depression in schizophrenia: evaluation based on specific assessment measures
Objectives
This study evaluated the rate of depressive symptoms in a sample of schizophrenic
patients. We examined the relationship between clinical-demographic features
and depressive symptoms.
Methods
The sample consisted in 88 patients who met the DSM-IV-TR criteria for
schizophrenia. Patients were divided into two subgroups on the basis of the
presence of depressive symptoms according to the Calgary Depression Scale
for Schizophrenia (CDSS > 6). The subjects were also assessed with
the Positive and Negative Syndrome Scale (PANSS), the Comprehensive Psychopathological
Rating Scale (CPRS), the Clinical Global Impression-Severity (CGI-1), the
Social and Occupational Functioning Assessment Scale (SOFAS), the Quality
of Life Scale (QLS), and the Disability Scale (DISS). Logistic regression
was used to identify critical clinical and demographic parameters associated
with depression in schizophrenic patients.
Results
Thirty-six percent of the subjects had depressive symptoms. Stepwise logistic
regression including clinical-demographic parameters showed that only three
parameters were significantly associated with depressive symptoms: the CGI-1,
the DISS and the PANSS-negative subscale.
Conclusions
Depressive symptoms are common in schizophrenic patients and are correlated
with a poor functional outcome, increased negative symptoms and severity of
the illness.