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A. Bada', U. Albert, G. Maina, F. Bogetto- Vol. 6, Dicembre 2000, num.4

Testo Immagini Bibliografia Summary Riassunto Indice

Influenza del genere sulla espressività clinica del disturbo delirante
Gender effects on clinical features in delusional disorder

Few studies have been performed aimed at characterizing patients with a DSM-IV diagnosis of Delusional Disorder (DD).

Objective
The present study was aimed at evaluating in a sample of 35 patients:
1. the prevalence of DD according to gender and,
2. gender-related clinical differences.

Methods
All patients had to meet DSM-IV criteria for DD to be admitted to the study. Moreover, patients were included only if, at the Brown Assessment of Beliefs Scale (BABS), they had a total score >18 and a score equal to 4 at the first item of this scale. All patients underwent a semistructured interview and several rating scales were used (BABS, SASS, HDRS, HARS). Patients were divided in two groups according to gender; demographic and clinical features were then compared.

Results
Our sample comprised 12 males (34.3%) and 23 females (65.7%), with a male to female ratio of 1 to 2. Most of the demographic and clinical features considered in our study resulted similar in both sexes, without statistical ly significant differences. Females tended to have an earlier age at onset of the disorder (37.5 ± 10.6 vs. 39.3 ± 12.8 years), while males an earlier age at first psychiatric visit (41.8 ± 12.7 vs. 45.4 ± 14.5 years), although these differences did not reach statistical significance. Females, moreover, tended to have more frequent and severe life events prior to DD onset, and more present and lifetime comorbid axis I disorders.

Discussion
Our data suggest that, in clinical samples, DD is more frequent in females than in males. The analysis of demographic and clinical features of the disorder seem to suggest that DD is a homogeneous nosographic category, although our data need to be replicated in larger samples in order to augment statistical power.