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R. Delle Chiaie, P. Pancheri - Vol. 5, Marzo1999, num.1

Testo Immagini Bibliografia Summary Riassunto Indice

Analisi combinata di due studi controllati, multicentrici, in doppio cieco per la valutazione di efficacia e tollerabilità di SAMe vs. placebo (MC1) e di SAMe vs. clomipramina (MC2) nel trattamento della depressione maggiore
Combined analysis of two controlled, multicentric, double blind studies to assess efficacy and safety of Sulfo-Adenosyl-Methionine (SAMe) vs. placebo (MC1) and SAMe vs. clomipramine (MC2) in the treatment of Major Depression

1 Cantoni GL.
S-adenosylmethionine: a new intermediate formed enzymatically from L-methionine and adenosine triphosphate.
Journal of Biological Chemistry 1953;204:403-416.

2 Mudd SH, Cantoni GL.
Biological transmethylation methyl-group neogenesis and other "one carbon metabolic reaction dependant upon tetrahydrofolic acid".
In: Florkin M, Stotz EH, eds. Comprehensive biochemistr.y vol. 15. New York: Elsevier 1964:1-47.

3 Bottiglieri T, Chary TKN, Carney MWP, e Coll.
Cerebrospinal fluid S-adenosylmethionine in depression and dementia: the effect of parenteral and oral treatment.
Journal of Neurology, Neurosurgery and Psychiatry 1990;53:1096-1098.

4 Tolbert LC.
MAT kinetics in affective disorders and schizophrenia: an account.
Alabama Journal of Medical Sciences 1988;25:291-295.

5 Bottiglieri T, Hyland K, Reynolds EH.
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders.
Drugs 1994;48:137-152.

6 Spillmann M, Fava M.
S-adenosylmethionine (Ademetionine) in psychiatric disorders. Historical perspective and current status.
CNS Drugs 1996;6:416-428.

7 Curcio M, Catto E, Stramentinoli G, e Coll.
Effect of S-adenosylmethionine on serotonin metabolism in rat brain.
Progress in Neuro-Psychpharmacology 1978;2:65-71.

8 Otero-Losada ME, Rubio MC.
Acute changes in 5-HT metabolism after S-adenosylmethionine administration.
General Pharmacology 1989;20:403-406.

9 Otero-Losada ME, Rubio MC.
Acute effects of S-adenosylmethionine on catecholaminergic central function.
European Journal of Pharmacology 1989;163:353-356.

10 Algeri S, Catto E, Curcio M, e Coll.
Changes in rat brain noradrenaline and serotonin after administration of S-adenosylmethionine.
In: Zappia V, Usdin E, Salvatore S, eds. Biochemical and pharmacological roles adenosylmethionine and the central nervous system. New York: Pergamon Press 1979:81-87.

11 Mishima K, Higuchi H, Kamata M, e Coll.
Effect of acute and cronic S-adenosylmethionine (SAM) administration on dopaminergic function in rat striatum.
Proceedings of the 15-th JSBP 1994:714 (abs.).

12 Bottiglieri T, Hyland K.
Effect of S-adenosylmethionine on dopamine metabolism in the rat striatum: an in vivo microdialysis study.
Society of Neurosciences Abstracts 1996;2:834.

13 Cohen B, Stramentinoli G, Sosa AL, e Coll.
Effect of the novel antidepressant S-adenosylmethionine on a1 and b-adrenoceptors in rat brain.
European Journal of Pharmacology 1989;170:201-207.

14 Di Perri B, Calderini G, Battistella A.
Phospholipid methylation increases [3H]diazepam and [3H]GABA binding in membranes from rat cerebellum.
Journal of Neurochemistry 1983;41:302-308.

15 Cimino M, Vantini G, Algeri S.
Age modification of dopaminergic and b-adrenergic receptor system: restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine.
Life sciences 1984;34:2029-2039.

16 Muccioli G, Scordamaglia A, Bertacco S, e Coll.
Efect of S-adenosylmethionine on brain muscarinic receptors.
European Journal of Pharmacology 1992;227:293-299.

17 Pancheri P, Racagni G, Delle Chiaie R, Popoli M.
Nuove acquisizioni sperimentali e cliniche sulla efficacia e tollerabilità della Ademetionina come antidepressivo.
Giornale Italiano di Psicopatologia 1997;2:138-160.

18 Hyman SE, Nestler EJ.
Initiation and adaptation: a paradigm for understanding psychotropic drug action.
American Journal of Psychiatry 1996;153:151-162.

19 Zanotti S, Mori S, Redaelli R, e Coll.
Modifications in brain cAMP- and calcium/calmodulin dependent protein kinases induced by treatment with S-adenosylmethionine.
Neuropharmacology 1998;37:1081-1089.

20 Fazio C, Andreoli V, Agnoli A, Casacchia M, Cerbo R.
Effetti terapeutici e meccanismo d’azione della S-adenosil-l-metionina (SAMe) nelle sindromi depressive.
Minerva Medica 1973;64:1515-1529.

21 Bressa GM.
S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies.
Acta Neurologica Scandinavica Supplementum 1994;89:7-14.

21 Delle Chiaie R, Boissard G, Pancheri P.
Paper presented at CINPP Congress, Nice 1997.

22 Macher JR.
A double-blind, placebo-controlled trial of intravenous ademetionine (SAMe) in the treatment of major depression (DSM III-R).
International Clinical Psycopharmacology (in press).

23 Danish University Antidepressant Group (DUAG).
Paroxetine: a selective serotonin riuptake inhibitor showing better tolerance, but weaker antidepressant effect than clomipramine in a controlled multicenter study.
Journal of Affective Disorders 1990;18:289-299.

24 Danish University Antidepressant Group (DUAG).
Citalopram: clinical effect profile in comparison with clomipramine. A controlled multicenter study.
Psychopharmacology 1986;90:131-138.

25 Danish University Antidepressant Group (DUAG).
Moclobemide: a reversible MAO-A-inhibitor showing weaker antidepressant effect than clomipramine in a controlled multicenter study.
Journal of Affective Disorders 1993;28:105-116.

26 American Psychiatric Association.
Diagnostic and Statistical Manual for Mental Disorders.
(III-rd Edition Revised). Washington DC: American Psychiatric Press 1984.

27 Paykel ES, Hollyman JA, Freeling P.
Predictors of therapeutic benefit from amitryptiline in mild depression: a general practice placebo-controlled trial.
Journal of Affective Disorders 1988;14:83-95.

28 Ottovanger EA.
The efficacy of fluvoxamine in patients with severe depression.
Progress in Neuropsychopharmacology and Biological Psychiatry 1994;18:731-740.

29 O’Sullivan RL, Fava M, Augustin C.
Sensitivity of the six item Hamilton Depression Rating Scale.
Acta Psychiatrica Scandinavica 1997;95:379-384.

30 Entsuash AR, Rudolph RL, Chitra R.
Effectivness of venlafaxine treatment in a broad spectrum of depressed patients: a meta-analysis.
Psychopharmacology Bulletin 1995;31:759-776.

31 Elkin I, Shea MT, Watkins JT.
National Institute of Mental Health Treatment of Depression Collaborative Research Program: General effectiveness of treatments.
Archives of General Psychiatry 1989;46:971-982.

32 Angst J, Bech P, Boyer P.
Consensus Conference on the Methodology of Clinical Trias of Antidepressants. Zurich, march 1988: report of the Consensus Committee.
Pharmacopsychiatry 1989;22:3-7.

33 Marcus RN, Mendels J.
Nefazodone in the treatment of severe, melancholic and recurrent depression.
Journal of Clinical Psychiatry 1996;57(suppl 2):19-23.