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V. MANNA, M.T. DANIELE,M. PINTO - Vol. 10, March 2004, Issue 1

Testo Bibliografia Summary Indice

Fattori ezio-patogenetici del disturbo borderline di personalità
Etio-pathogenetic factors of the Borderline Personality Disorder

In the last few years, many clinical and experimental studies investigated the role of different factors in the etiology and pathogenesis of the Borderline Personality Disorder (BPD). In the search of the BPD etio-pathogenesis the relative importance of biological, psychological and social factors were evidenced by different Authors, with divergent theoretical approach to the mental disease. So, childhood life events, childhood sexual and physical abuse, affective disorders, impulse disorders, dissociative disorders, post-traumatic aspects of the behaviour and organic brain dysfunctions were considered important factors in the genesis of the personality disorder. The role and the significance of selected neuropsychiatric abnormalities in the etiology of borderline personality disorder seems related strongly to the theoretical point of view of the different Authors. The interaction of heredity and childhood environment results relevant in the genesis of the BPD. Behaviours analogous to frontal lobe dysfunction in children with attention deficit/hyperactivity disorder and in patients with BPD were evidenced. In this update review, a psychobiological theory of borderline personality disorder is presented in the light of the hedonic homeostatic dysregulation (dysedonia). Some critical considerations about diagnostic validity in psychiatric illness and a heuristic approach to the etiology of the human psychopathology were also proposed.