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U. ALBERT, C. BERGESIO, V. LASAPONARA, G. MAINA, F. BOGETTO - Vol. 9, December 2003, Issue 4

Testo Immagini Bibliografia Summary Indice

Disturbi di personalità nel disturbo di panico con e senza agorafobia
Personality disorders in panic disorder with and without agoraphobia

Objective
Panic Disorder (PD) and the development of agoraphobia appear to have a clear linkage. The present study focused the attention on the role of Axis II comorbidity in predisposing agoraphobia; we compared patients with PD and agoraphobia (PDA) to subjects without agoraphobia (PDN) for the presence of personality disorders.

Methods
86 out-patients with a principal diagnosis of PD (DSM-IV; SCID) were included in the present study: of them 51 with and 35 without agoraphobia. All patients were assessed using a semistructured clinical interview for: 1) socio-demographic data; 2) Axis I and Axis II diagnosis (SCID-I and II); 3) clinical features of PD. For statistical comparison the sample was split into two groups according to the presence or absence of agoraphobia.

Results
No differences were observed in socio-demographic features. Patients with agoraphobia showed an earlier age at PD onset. PDA displayed a significantly higher prevalence of personality disorders than did patients without agoraphobia. Statistical analysis showed borderline and histrionic personality disorders significantly associated with agoraphobia and dependent personality disorder with a trend toward significance.

Conclusions
Our study confirms early onset as a risk factor for the development of agoraphobia; moreover it suggests that personality disorders might predispose to agoraphobia.