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S. BELLINO, L. PATRIA, R. DI LORENZO, E. PARADISO, F. BOGETTO - Vol. 9, March 2003, Issue 1

Testo Immagini Bibliografia Summary Indice

Comorbilità di Asse I nel disturbo borderline di personalità: un’indagine clinica in pazienti con disturbi depressivi
Axis I comorbidity in borderline personality disorder: a clinical investigation of patients with depressive disorders

Objectives
Clinical presentation of borderline personality disorder (BPD) is characterized by high frequency of Axis I comorbidity. The most common comorbid disorders are depressive disorders. The aim of this study is to assess demographic and clinical characteristics of a group of patients with depressive disorders and concomitant BPD, compared with a control group with depressive disorders and other personality disorders (PDs).

Methods
101 consecutive outpatients receiving a diagnosis of depressive disorder and a codiagnosis of personality disorder were included. Patients were assessed using: a semistructured interview for demographic and clinical features; the Structured Interview for DSM-IV (SCID); Hamilton scales for anxiety and depression; Zung depression self-rating scale; the Borderline Syndrome Index (BSI); the Social Functional Assessment Scale (SOFAS); the Revised Childhood Experiences Questionnaire (CEQ-R) to search for mental, physical and sexual abuse in childhood.
A logistic regression analysis was performed using BSI score as the dependent variable.

Results
Symptom severity of BPD (BSI score) was related to five factors: Zung depression self-rating scale score; SOFAS score; presence of self-mutilating behaviors; mental abuse experienced in childhood; familiarity for mood disorders.

Conclusions
Comorbidity of depressive disorders and BPD can be considered a distinct clinical condition characterized by specific features.