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I. Maremmani, M. Pacini, S. Canoniero, S. Lubrano, J.A. Deltito, J.M. Palumbo - Vol. 8, March 2002, Issue 1

Testo Bibliografia Summary Indice

Indicazioni psichiatriche degli antagonisti degli oppiacei
Opioid-receptor antagonists in Psychiatry

Naltrexone has proved useful in a variety of psychopathological states. Mainly it has been used in long term therapy of heroin addicts. More recently it has been addressed to the treatment of alcoholics. Anecdoctical observations and research data suggest its use also in the field of Mental Illnesses (Eating disorders, Gilles de la Tourette syndrome and Obsessive Compulsive Disorder, Schizophrenia, Self Injuring Behaviours, Autism, Tricotillomania, Post-traumatic stress disorder). In this paper we will briefly discuss the use of opioid antagonists in drug addicts and then we will review the evidence for future development for other psychiatric illnesses. Examined data suggest that opioid antagonists be effective on symptomathologic clusters common to different clinical entities.