Objectives
The aim of this article is to explain the nutrients that play an active role in the pathophysiology of schizophrenia.
Methods
This paper is a narrative literature review of relevant articles and prior works that have been central to the topic including the active nutrients in the pathophysiology of schizophrenia.
Results
The findings are compiled under six headings. The changes in the antioxidant defense system, dopamine pathway, serotonin pathway, gamma-aminobutyric acid (GABA) pathway, glutamate pathway, the endocannabinoid system, and metabolomic profile were investigated in relation to nutrients.
Conclusions
This review provides an update of scientific knowledge on the growing role of nutrition in schizophrenia. Nutrient deficiencies that occur frequently in these patients should be followed and eliminated to ensure the correct functioning of the pathophysiological pathways of the disease.